Stage 5

Stage 5 is the most advanced stage of Parkinson’s disease. Advanced stiffness in the legs can also cause freezing upon standing, making it impossible to stand or walk. People in this stage require wheelchairs, and they’re often unable to stand on their own without falling. Around-the-clock assistance is required to prevent falls.

Up to 30 percent of people at stage 4 and 5 experience confusion, hallucinations, and delusions. Hallucinations occur when you see things that aren’t there. Delusions happen when you believe things that aren’t true, even when you have been presented with evidence that your belief is wrong. Dementia is also common, affecting up to 75 percent of people with Parkinson’s. Side effects from medications at these later stages can often outweigh the benefits.

Alternative rating system

One complaint about the Hoehn and Yahr rating system is that it focuses solely on symptoms of movement. There are other types of symptoms associated with Parkinson’s disease, such as intellectual impairment.

Because of this, many doctors may also use the Unified Parkinson’s Disease Rating Scale. It allows them to rate cognitive difficulties that may impair day-to-day tasks and the effectiveness of treatment.

This scale is much more complicated, but it’s also more thorough. It allows doctors to take into account a more complete picture that examines the person’s entire state of health instead of just motor symptoms.

Nonmotor symptoms

The progression of Parkinson’s disease is most commonly evaluated by motor symptoms such as muscle stiffness and tremors. However, nonmotor symptoms are also common. Some people will develop these symptoms years before developing Parkinson’s, and some will develop them after. Anywhere from 80 to 90 percent of people with Parkinson’s disease will also experience nonmotor symptoms.

Nonmotor symptoms include:

  • cognitive changes, such as difficulties with memory or planning, or slowing of thought
  • mood disorders such as anxiety and depression
  • sleep disorders such as insomnia
  • fatigue
  • constipation
  • vision problems
  • speech and swallowing problems
  • difficulties with sense of smell

Nonmotor symptoms may require additional treatment in many people. These symptoms can advance as the disease progresses.

Is Parkinson’s disease fatal?

Parkinson’s disease itself doesn’t cause death. However, symptoms related to Parkinson’s can be fatal. For example, injuries that occur because of a fall or problems associated with dementia can be fatal.

Some people with Parkinson’s experience difficulty swallowing. This can lead to aspiration pneumonia. This condition is caused when foods, or other foreign objects, are inhaled into the lungs.

What you can do

As of 2017, there is no definite cure for Parkinson’s disease. There is also no definite known cause. It’s likely due to a combination of an individual’s susceptibility and environmental factors. Most cases of Parkinson’s disease happen without a genetic link. Only 10 percent of people with Parkinson’s report having a family member with the disease. Many toxins are suspected and have been studied, but no single substance can be reliably linked to Parkinson’s. However, research is ongoing. It’s estimated that twice as many men have the disease compared to women.

Ultimately, understanding both the motor and nonmotor symptoms of Parkinson’s can prompt earlier detection — and therefore earlier treatment. This can improve quality of life.

Knowing your own individual risk factors can help you detect symptoms in the beginning stages. Keep in mind that not all people progress to the most severe stages of Parkinson’s. The disease can vary greatly among individuals.

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