Celebrities with high-stress, high-profile careers aren’t immune to the heartburn and indigestion of GERD.

Do you struggle with gastroesophageal reflux disease, known as GERD or acid reflux? You’re in good company. According to the American College of Gastroenterology, more than 60 million Americans experience heartburn at least once a month and more than 15 million have symptoms every day. Not surprisingly, many celebrities suffer from acid reflux too. See which famous people from the 50-yard line to 1600 Pennsylvania Ave. have wrestled with GERD.

In 2004, Jessica’s little sister, then 20, appeared on “Saturday Night Live” and had a lip-synching disaster of epic proportions. A prerecorded vocal track began playing during what was supposed to be a live performance. At first Simpson blamed her band for cuing the wrong song. But two days later on Ryan Seacrest’s radio show, her father and manager, Joe Simpson, explained that she had a sore throat from acid reflux and couldn’t sing. That’s why she had arranged to lip-synch. To avoid further embarrassing episodes, Ashlee herself changed her diet to avoid dairy and eats nothing after 9 p.m. She keeps silent for an hour before going on stage. It also helps her indigestion to keep her head propped up when she sleeps.

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Brett Favre, 44, the gridiron ironman who took the Green Bay Packers to the Super Bowl twice, winning XXXI, is among the many celebrities who suffer from acid reflux. He openly talked about his acid reflux in the commercial he made for Prilosec OTC, a proton pump inhibitor (PPI) often used to treat heartburn. In the commercial, he says that frequent heartburn is “no big deal” thanks to his taking one pill a day. Resistant to retiring, Favre had one of the longer pro careers, finishing with the New York Jets and then the Minnesota Vikings in 2010. He remains the NFL starting quarterback with the most regular-season wins.

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